The following was published on August 20, 2009 in a local newspaper:
"Republic of the Philippines
Department of Health
OFFICE OF THE SECRETARY
ADVISORY
SubJECT SEVEN COLOR CRYSTAL BALLS
The Department of Health received reports of the proliferation of a product called seven color crystal balls. The public is advised to keep this product away from children since it is not a toy. The product may pose a hazard as this may be swallowed accidentally. For inquiries, please call the Department of Health at 743-8301 local 3408 or 711-6824.
(Sgd) FRANCISCO T. DUQUE III, M.D., MSc.
Secretary of Health"
Antioxidants
http://www.nlm.nih.gov/medlineplus/antioxidants.html
Antioxidants are substances that may protect your cells against the effects of free radicals. Free radicals are molecules produced when your body breaks down food, or by environmental exposures like tobacco smoke and radiation. Free radicals can damage cells, and may play a role in heart disease, cancer and other diseases.
Antioxidant substances include
* Beta-carotene
* Lutein
* Lycopene
* Selenium
* Vitamin A
* Vitamin C
* Vitamin E
Antioxidants are found in many foods. These include fruits and vegetables, nuts, grains, and some meats, poultry and fish.
* Overviews
o Antioxidant Vitamins(American Heart Association)
o What Is an Antioxidant?(American Dietetic Association)
* Latest News
o Antioxidants Pose No Melanoma Threat(08/17/2009, HealthDay)
o Studies Show Genetic Activity of Antioxidants(07/21/2009, HealthDay)
o Antioxidant May Boost Exercise Endurance(06/29/2009, Reuters Health)
* Specific Conditions
o CranberryFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o Grape Seed ExtractFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o Lycopene: An Antioxidant for Good Health(American Dietetic Association)
o NoniFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o SeleniumFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o Vitamin A and CarotenoidsFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o Vitamin C (Ascorbic Acid)(Merck & Co., Inc.)
o Vitamin EFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o ZincFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
* Related Issues
o Antioxidant Therapies for Cystic Fibrosis(Cystic Fibrosis Foundation)
o Antioxidants: An Answer to Aging?(American Dietetic Association)
o Coenzyme Q10 (PDQ)From the National Institutes of Health(National Cancer Institute)
* Clinical Trials
o ClinicalTrials.gov: AntioxidantsFrom the National Institutes of Health(National Institutes of Health)
* Research
o Antioxidants, Over Time, Support Aging Minds(Agricultural Research Service)
o Drinking Black Tea Shows No Impact on Cardiovascular Risk FactorsFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
* Journal Articles
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
o Article: Treatment regimens for non-alcoholic fatty liver disease.
o Article: [Preclinical and clinical studies of the efficacy of Panavir in...
o Article: Intake of vitamin C and E in pregnancy and risk...
o Antioxidants -- see more articles
* Directories
o Nutrient Lists(Dept. of Agriculture) - PDF
* Organizations
o Food and Nutrition Information Center
o National Institutes of Health, Office of Dietary SupplementsFrom the National Institutes of Health
* Specific Conditions
o CranberryFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o Grape Seed ExtractFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o Lycopene: An Antioxidant for Good Health(American Dietetic Association)
o NoniFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o SeleniumFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o Vitamin A and CarotenoidsFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o Vitamin C (Ascorbic Acid)(Merck & Co., Inc.)
o Vitamin EFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o ZincFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
* Related Issues
o Antioxidant Therapies for Cystic Fibrosis(Cystic Fibrosis Foundation)
o Antioxidants: An Answer to Aging?(American Dietetic Association)
o Coenzyme Q10 (PDQ)From the National Institutes of Health(National Cancer Institute)
* Clinical Trials
o ClinicalTrials.gov: AntioxidantsFrom the National Institutes of Health(National Institutes of Health)
* Research
o Antioxidants, Over Time, Support Aging Minds(Agricultural Research Service)
o Drinking Black Tea Shows No Impact on Cardiovascular Risk FactorsFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
* Journal Articles
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
o Article: Treatment regimens for non-alcoholic fatty liver disease.
o Article: [Preclinical and clinical studies of the efficacy of Panavir in...
o Article: Intake of vitamin C and E in pregnancy and risk...
o Antioxidants -- see more articles
* Directories
o Nutrient Lists(Dept. of Agriculture) - PDF
* Organizations
o Food and Nutrition Information Center
o National Institutes of Health, Office of Dietary SupplementsFrom the National Institutes of Health
* Latest News
o Antioxidants Pose No Melanoma Threat(08/17/2009, HealthDay)
o Studies Show Genetic Activity of Antioxidants(07/21/2009, HealthDay)
o Antioxidant May Boost Exercise Endurance(06/29/2009, Reuters Health)
* Specific Conditions
o CranberryFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o Grape Seed ExtractFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o Lycopene: An Antioxidant for Good Health(American Dietetic Association)
o NoniFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
o SeleniumFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o Vitamin A and CarotenoidsFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o Vitamin C (Ascorbic Acid)(Merck & Co., Inc.)
o Vitamin EFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
o ZincFrom the National Institutes of Health(National Institutes of Health, Office of Dietary Supplements)
* Related Issues
o Antioxidant Therapies for Cystic Fibrosis(Cystic Fibrosis Foundation)
o Antioxidants: An Answer to Aging?(American Dietetic Association)
o Coenzyme Q10 (PDQ)From the National Institutes of Health(National Cancer Institute)
* Clinical Trials
o ClinicalTrials.gov: AntioxidantsFrom the National Institutes of Health(National Institutes of Health)
* Research
o Antioxidants, Over Time, Support Aging Minds(Agricultural Research Service)
o Drinking Black Tea Shows No Impact on Cardiovascular Risk FactorsFrom the National Institutes of Health(National Center for Complementary and Alternative Medicine)
* Journal Articles
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
o Article: Treatment regimens for non-alcoholic fatty liver disease.
o Article: [Preclinical and clinical studies of the efficacy of Panavir in...
o Article: Intake of vitamin C and E in pregnancy and risk...
o Antioxidants -- see more articles
* Directories
o Nutrient Lists(Dept. of Agriculture) - PDF
* Organizations
o Food and Nutrition Information Center
o National Institutes of Health, Office of Dietary SupplementsFrom the National Institutes of Health
http://www.allaboutyou.com/
allaboutyou web site
Wednesday, August 19, 2009
Monday, August 10, 2009
Advisory re Bangus restaurant at unit 127-128 North Arcade, SM Mall of Asia, Pasay City. I sent
a request to said restaurant for information about said restaurant. Based on evidence, said
request for information was received by said restaurant's agent. Said restaurant has not
provided the requested information.
National Center for Complementary and Alternative Medicine
An Introduction to Probiotics
Probiotics are live microorganisms (in most cases, bacteria) that are similar to
beneficial microorganisms found in the human gut. They are also called
“friendly bacteria” or “good bacteria.” Probiotics are available to consumers
mainly in the form of dietary supplements and foods. They can be used as
complementary and alternative medicine (CAM).1
Key Points
• People use probiotic products as CAM to prevent and treat certain illnesses
and support general wellness.
• There is limited evidence supporting some uses of probiotics. Much more
scientific knowledge is needed about probiotics, including about their safety
and appropriate use.
• Effects found from one species or strain of probiotics do not necessarily
hold true for others, or even for different preparations of the same species
or strain.
• Tell your health care providers about any CAM practices you use. Give them
a full picture of what you do to manage your health. This will help ensure
coordinated and safe care. For tips for talking with your health care
providers about CAM, see NCCAM’s Time to Talk campaign at
nccam.nih.gov/timetotalk/.
What Probiotics Are
Experts have debated how to define probiotics. One widely used definition,
developed by the World Health Organization and the Food and Agriculture
Organization of the United Nations, is that probiotics are “live microorganisms,
which, when administered in adequate amounts, confer a health benefit on the
host.” (Microorganisms are tiny living organisms—such as bacteria, viruses, and
yeasts—that can be seen only under a microscope.)
1
CAM is a group of diverse medical and health care systems, practices, and products that are not
presently considered to be part of conventional medicine. Complementary medicine is used
together with conventional medicine, and alternative medicine is used in place of conventional
medicine. Some health care providers practice both CAM and conventional medicine.
Probiotics are not the same thing as prebiotics—nondigestible food ingredients that selectively
stimulate the growth and/or activity of beneficial microorganisms already in people’s colons.
When probiotics and prebiotics are mixed together, they form a synbiotic.
Probiotics are available in foods and dietary supplements (for example, capsules, tablets,
and powders) and in some other forms as well. Examples of foods containing probiotics
are yogurt, fermented and unfermented milk, miso, tempeh, and some juices and soy
beverages. In probiotic foods and supplements, the bacteria may have been present
originally or added during preparation.
Most probiotics are bacteria similar to those naturally found in people’s guts, especially
in those of breastfed infants (who have natural protection against many diseases). Most
often, the bacteria come from two groups, Lactobacillus or Bifidobacterium. Within each
group, there are different species (for example, Lactobacillus acidophilus and Bifidobacterium
bifidus), and within each species, different strains (or varieties). A few common
probiotics, such as Saccharomyces boulardii, are yeasts, which are different from bacteria.
Some probiotic foods date back to ancient times, such as fermented foods and cultured
milk products. Interest in probiotics in general has been growing; Americans’ spending
on probiotic supplements, for example, nearly tripled from 1994 to 2003.
Uses for Health Purposes
There are several reasons that people are interested in probiotics for health purposes.
First, the world is full of microorganisms (including bacteria), and so are people’s bodies—in
and on the skin, in the gut, and in other orifices. Friendly bacteria are vital to proper
development of the immune system, to protection against microorganisms that could cause
disease, and to the digestion and absorption of food and nutrients. Each person’s mix of
bacteria varies. Interactions between a person and the microorganisms in his body, and among
the microorganisms themselves, can be crucial to the person’s health and well-being.
This bacterial “balancing act” can be thrown off in two major ways:
1. By antibiotics, when they kill friendly bacteria in the gut along with unfriendly bacteria.
Some people use probiotics to try to offset side effects from antibiotics like gas, cramping,
or diarrhea. Similarly, some use them to ease symptoms of lactose intolerance—a
condition in which the gut lacks the enzyme needed to digest significant amounts of the
major sugar in milk, and which also causes gastrointestinal symptoms.
2. “Unfriendly” microorganisms such as disease-causing bacteria, yeasts, fungi, and
parasites can also upset the balance. Researchers are exploring whether probiotics could
halt these unfriendly agents in the first place and/or suppress their growth and activity in
conditions like:
• Infectious diarrhea
• Irritable bowel syndrome
NCCAM-2
----------------------- Page 3-----------------------
• Inflammatory bowel disease (e.g., ulcerative colitis and Crohn’s disease)
• Infection with Helicobacter pylori (H. pylori), a bacterium that causes most ulcers and
many types of chronic stomach inflammation
• Tooth decay and periodontal disease
• Vaginal infections
• Stomach and respiratory infections that children acquire in daycare
• Skin infections.
Another part of the interest in probiotics stems from the fact there are cells in the digestive
tract connected with the immune system. One theory is that if you alter the microorganisms in
a person’s intestinal tract (as by introducing probiotic bacteria), you can affect the immune
system’s defenses.
What the Science Says
Scientific understanding of probiotics and their potential for preventing and treating health
conditions is at an early stage, but moving ahead. In November 2005, a conference that was
cofunded by the National Center for Complementary and Alternative Medicine (NCCAM) and
convened by the American Society for Microbiology explored this topic.
According to the conference report, some uses of probiotics for which there is some
encouraging evidence from the study of specific probiotic formulations are as follows:
• To treat diarrhea (this is the strongest area of evidence, especially for diarrhea from rotavirus)
• To prevent and treat infections of the urinary tract or female genital tract
• To treat irritable bowel syndrome
• To reduce recurrence of bladder cancer
• To shorten how long an intestinal infection lasts that is caused by a bacterium called
Clostridium difficile
• To prevent and treat pouchitis (a condition that can follow surgery to remove the colon)
• To prevent and manage atopic dermatitis (eczema) in children.
The conference panel also noted that in studies of probiotics as cures, any beneficial effect was
usually low; a strong placebo effect often occurs; and more research (especially in the form of
large, carefully designed clinical trials) is needed in order to draw firmer conclusions.
Some other areas of interest to researchers on probiotics are
• What is going on at the molecular level with the bacteria themselves and how they may
interact with the body (such as the gut and its bacteria) to prevent and treat diseases.
Advances in technology and medicine are making it possible to study these areas much
better than in the past.
• Issues of quality. For example, what happens when probiotic bacteria are treated or are
added to foods—is their ability to survive, grow, and have a therapeutic effect altered?
NCCAM-3
• The best ways to administer probiotics for therapeutic purposes, as well as the best doses
and schedules.
• Probiotics’ potential to help with the problem of antibiotic-resistant bacteria in the gut.
• Whether they can prevent unfriendly bacteria from getting through the skin or mucous
membranes and traveling through the body (e.g., which can happen with burns, shock,
trauma, or suppressed immunity).
Side Effects and Risks
Some live microorganisms have a long history of use as probiotics without causing illness in
people. Probiotics’ safety has not been thoroughly studied scientifically, however. More
information is especially needed on how safe they are for young children, elderly people, and
people with compromised immune systems.
Probiotics’ side effects, if they occur, tend to be mild and digestive (such as gas or bloating).
More serious effects have been seen in some people. Probiotics might theoretically cause
infections that need to be treated with antibiotics, especially in people with underlying health
conditions. They could also cause unhealthy metabolic activities, too much stimulation of the
immune system, or gene transfer (insertion of genetic material into a cell).
Probiotic products taken by mouth as a dietary supplement are manufactured and regulated as
foods, not drugs.
Some Other Points To Consider
• If you are thinking about using a probiotic product as CAM, consult your health care
provider first. No CAM therapy should be used in place of conventional medical care or to
delay seeking that care.
• Effects from one species or strain of probiotics do not necessarily hold true for others, or
even for different preparations of the same species or strain.
• If you use a probiotic product and experience an effect that concerns you, contact your
health care provider.
• You can locate research reports in peer-reviewed journals on probiotics’ effectiveness and
safety through the resources PubMed and CAM on PubMed.
NCCAM-Sponsored Research on Probiotics
Among recent NCCAM-sponsored research are the following projects:
• Investigators at Tulane University School of Public Health and Tropical Medicine are
studying the effectiveness of selected probiotic agents to treat diarrhea in undernourished
children in a developing country.
NCCAM-4
• At the Mayo Clinic College of Medicine, researchers have been examining probiotics for
possibly decreasing the levels of certain substances in the urine that can cause problems
such as kidney stones.
• A team at Tufts-New England Medical Center is studying probiotics for treating an
antibiotic-resistant type of bacteria that causes severe infections in people who are
hospitalized, live in nursing homes, or have weakened immune systems.
References
Sources are primarily recent reviews on the general topic of probiotics in the peer-reviewed
medical and scientific literature in English in the PubMed database, selected evidence-based
databases, and Federal Government sources.
1994-2004 U.S. specialty/other supplement sales. Nutrition Business Journal. 2005. Accessed at http://www.nutritionbusiness.com
on December 7, 2006.
Alvarez-Olmos MI, Oberhelman RA. Probiotic agents and infectious diseases: a modern perspective on a traditional
therapy. Clinical Infectious Diseases. 2001;32(11):1567-1576.
Bifidobacteria. Natural Medicines Comprehensive Database Web site. Accessed at http://www.naturaldatabase.com on
December 7, 2006.
Bifidus. Thomson MICROMEDEX AltMedDex System Web site. Accessed at http://www.micromedex.com on December 7, 2006.
Cabana MD, Shane AL, Chao C, et al. Probiotics in primary care pediatrics. Clinical Pediatrics. 2006;45(5):405-410.
Doron S, Gorbach SL. Probiotics: their role in the treatment and prevention of disease. Expert Review of Anti-Infective
Therapy. 2006;4(2):261-275.
Ezendam J, van Loveren H. Probiotics: immunomodulation and evaluation of safety and efficacy. Nutrition Reviews.
2006;64(1):1-14.
Food and Agriculture Organization (FAO) of the United Nations and World Health Organization (WHO). Guidelines for the
Evaluation of Probiotics in Food. Report of a Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics
in Food. Accessed at http://www.who.int/foodsafety/fs_management/en/probiotic_guidelines.pdf on December 7, 2006.
Gill HS, Guarner F. Probiotics and human health: a clinical perspective. Postgraduate Medical Journal. 2004;80(947):516-526.
Hammerman C, Bin-Nun A, Kaplan M. Safety of probiotics: comparison of two popular strains. BMJ.
2006;333(7576):1006-1008.
Huebner ES, Surawicz CM. Probiotics in the prevention and treatment of gastrointestinal infections. Gastroenterology
Clinics of North America. 2006;35(2):355-365.
Lactobacillus. Natural Medicines Comprehensive Database Web site. Accessed at http://www.naturaldatabase.com on
December 7, 2006.
Lactobacillus. Thomson MICROMEDEX AltMedDex System Web site. Accessed at http://www.micromedex.com on
December 7, 2006.
Probiotics: Bottom Line Monograph. Natural Standard Database Web site. Accessed at http://www.naturalstandard.com on
December 7, 2006.
Reid G, Hammond JA. Probiotics: some evidence of their effectiveness. Canadian Family Physician. 2005;51:1487-1493.
Salminen SJ, Gueimonde M, Isolauri E. Probiotics that modify disease risk.Journal of Nutrition . 2005;135(5):1294-1298.
Vanderhoof JA, Young RJ. Current and potential uses of probiotics. Annals of Allergy, Asthma, & Immunology.
2004;93(5 suppl 3):S33-S37.
Walker R, Buckley M. Probiotic Microbes: The Scientific Basis. Report of an American Society for Microbiology colloquium;
November 5-7, 2005; Baltimore, Maryland. American Society for Microbiology Web site. Accessed at
http://www.asm.org/academy/index.asp?bid=43351 on December 7, 2006.
NCCAM-5
----------------------- Page 6-----------------------
For More Information
NCCAM Clearinghouse
The NCCAM Clearinghouse provides information on CAM and NCCAM, including
publications and searches of Federal databases of scientific and medical literature. The
Clearinghouse does not provide medical advice, treatment recommendations, or referrals
to practitioners.
Toll-free in the U.S.: 1-888-644-6226
TTY (for deaf and hard-of-hearing callers): 1-866-464-3615
Web site: nccam.nih.gov
E-mail: info@nccam.nih.gov
PubMed®
A service of the National Library of Medicine (NLM), PubMed contains publication information
and (in most cases) brief summaries of articles from scientific and medical journals. CAM on
PubMed, developed jointly by NCCAM and NLM, is a subset of the PubMed system and focuses
on the topic of CAM.
Web site: www.ncbi.nlm.nih.gov/sites/entrez
CAM on PubMed: nccam.nih.gov/camonpubmed/
Acknowledgments
NCCAM thanks the following people for their technical expertise and review of this publication:
Carol Wells, Ph.D., University of Minnesota Medical School; Richard Oberhelman, M.D., Tulane
University School of Public Health and Tropical Medicine; Patricia Hibberd, M.D., Ph.D., Tufts-
New England Medical Center; Richard Walker, Ph.D., U.S. Food and Drug Administration; and
Marguerite Klein, M.S., R.D., and Jonathan (Josh) Berman, M.D., Ph.D., NCCAM.
This publication is not copyrighted and is in the public domain.
Duplication is encouraged.
NCCAM has provided this material for your information. It is not intended to substitute
for the medical expertise and advice of your primary health care provider. We encourage
you to discuss any decisions about treatment or care with your health care provider. The
mention of any product, service, or therapy is not an endorsement by NCCAM.
National Institutes of Health
???
U.S. Department of Health and Human Services
D345
Created January 2007
Updated August 2008
*D345*
web site with useful, free information:
http://www.alwaysfrugal.com/
a request to said restaurant for information about said restaurant. Based on evidence, said
request for information was received by said restaurant's agent. Said restaurant has not
provided the requested information.
National Center for Complementary and Alternative Medicine
An Introduction to Probiotics
Probiotics are live microorganisms (in most cases, bacteria) that are similar to
beneficial microorganisms found in the human gut. They are also called
“friendly bacteria” or “good bacteria.” Probiotics are available to consumers
mainly in the form of dietary supplements and foods. They can be used as
complementary and alternative medicine (CAM).1
Key Points
• People use probiotic products as CAM to prevent and treat certain illnesses
and support general wellness.
• There is limited evidence supporting some uses of probiotics. Much more
scientific knowledge is needed about probiotics, including about their safety
and appropriate use.
• Effects found from one species or strain of probiotics do not necessarily
hold true for others, or even for different preparations of the same species
or strain.
• Tell your health care providers about any CAM practices you use. Give them
a full picture of what you do to manage your health. This will help ensure
coordinated and safe care. For tips for talking with your health care
providers about CAM, see NCCAM’s Time to Talk campaign at
nccam.nih.gov/timetotalk/.
What Probiotics Are
Experts have debated how to define probiotics. One widely used definition,
developed by the World Health Organization and the Food and Agriculture
Organization of the United Nations, is that probiotics are “live microorganisms,
which, when administered in adequate amounts, confer a health benefit on the
host.” (Microorganisms are tiny living organisms—such as bacteria, viruses, and
yeasts—that can be seen only under a microscope.)
1
CAM is a group of diverse medical and health care systems, practices, and products that are not
presently considered to be part of conventional medicine. Complementary medicine is used
together with conventional medicine, and alternative medicine is used in place of conventional
medicine. Some health care providers practice both CAM and conventional medicine.
Probiotics are not the same thing as prebiotics—nondigestible food ingredients that selectively
stimulate the growth and/or activity of beneficial microorganisms already in people’s colons.
When probiotics and prebiotics are mixed together, they form a synbiotic.
Probiotics are available in foods and dietary supplements (for example, capsules, tablets,
and powders) and in some other forms as well. Examples of foods containing probiotics
are yogurt, fermented and unfermented milk, miso, tempeh, and some juices and soy
beverages. In probiotic foods and supplements, the bacteria may have been present
originally or added during preparation.
Most probiotics are bacteria similar to those naturally found in people’s guts, especially
in those of breastfed infants (who have natural protection against many diseases). Most
often, the bacteria come from two groups, Lactobacillus or Bifidobacterium. Within each
group, there are different species (for example, Lactobacillus acidophilus and Bifidobacterium
bifidus), and within each species, different strains (or varieties). A few common
probiotics, such as Saccharomyces boulardii, are yeasts, which are different from bacteria.
Some probiotic foods date back to ancient times, such as fermented foods and cultured
milk products. Interest in probiotics in general has been growing; Americans’ spending
on probiotic supplements, for example, nearly tripled from 1994 to 2003.
Uses for Health Purposes
There are several reasons that people are interested in probiotics for health purposes.
First, the world is full of microorganisms (including bacteria), and so are people’s bodies—in
and on the skin, in the gut, and in other orifices. Friendly bacteria are vital to proper
development of the immune system, to protection against microorganisms that could cause
disease, and to the digestion and absorption of food and nutrients. Each person’s mix of
bacteria varies. Interactions between a person and the microorganisms in his body, and among
the microorganisms themselves, can be crucial to the person’s health and well-being.
This bacterial “balancing act” can be thrown off in two major ways:
1. By antibiotics, when they kill friendly bacteria in the gut along with unfriendly bacteria.
Some people use probiotics to try to offset side effects from antibiotics like gas, cramping,
or diarrhea. Similarly, some use them to ease symptoms of lactose intolerance—a
condition in which the gut lacks the enzyme needed to digest significant amounts of the
major sugar in milk, and which also causes gastrointestinal symptoms.
2. “Unfriendly” microorganisms such as disease-causing bacteria, yeasts, fungi, and
parasites can also upset the balance. Researchers are exploring whether probiotics could
halt these unfriendly agents in the first place and/or suppress their growth and activity in
conditions like:
• Infectious diarrhea
• Irritable bowel syndrome
NCCAM-2
----------------------- Page 3-----------------------
• Inflammatory bowel disease (e.g., ulcerative colitis and Crohn’s disease)
• Infection with Helicobacter pylori (H. pylori), a bacterium that causes most ulcers and
many types of chronic stomach inflammation
• Tooth decay and periodontal disease
• Vaginal infections
• Stomach and respiratory infections that children acquire in daycare
• Skin infections.
Another part of the interest in probiotics stems from the fact there are cells in the digestive
tract connected with the immune system. One theory is that if you alter the microorganisms in
a person’s intestinal tract (as by introducing probiotic bacteria), you can affect the immune
system’s defenses.
What the Science Says
Scientific understanding of probiotics and their potential for preventing and treating health
conditions is at an early stage, but moving ahead. In November 2005, a conference that was
cofunded by the National Center for Complementary and Alternative Medicine (NCCAM) and
convened by the American Society for Microbiology explored this topic.
According to the conference report, some uses of probiotics for which there is some
encouraging evidence from the study of specific probiotic formulations are as follows:
• To treat diarrhea (this is the strongest area of evidence, especially for diarrhea from rotavirus)
• To prevent and treat infections of the urinary tract or female genital tract
• To treat irritable bowel syndrome
• To reduce recurrence of bladder cancer
• To shorten how long an intestinal infection lasts that is caused by a bacterium called
Clostridium difficile
• To prevent and treat pouchitis (a condition that can follow surgery to remove the colon)
• To prevent and manage atopic dermatitis (eczema) in children.
The conference panel also noted that in studies of probiotics as cures, any beneficial effect was
usually low; a strong placebo effect often occurs; and more research (especially in the form of
large, carefully designed clinical trials) is needed in order to draw firmer conclusions.
Some other areas of interest to researchers on probiotics are
• What is going on at the molecular level with the bacteria themselves and how they may
interact with the body (such as the gut and its bacteria) to prevent and treat diseases.
Advances in technology and medicine are making it possible to study these areas much
better than in the past.
• Issues of quality. For example, what happens when probiotic bacteria are treated or are
added to foods—is their ability to survive, grow, and have a therapeutic effect altered?
NCCAM-3
• The best ways to administer probiotics for therapeutic purposes, as well as the best doses
and schedules.
• Probiotics’ potential to help with the problem of antibiotic-resistant bacteria in the gut.
• Whether they can prevent unfriendly bacteria from getting through the skin or mucous
membranes and traveling through the body (e.g., which can happen with burns, shock,
trauma, or suppressed immunity).
Side Effects and Risks
Some live microorganisms have a long history of use as probiotics without causing illness in
people. Probiotics’ safety has not been thoroughly studied scientifically, however. More
information is especially needed on how safe they are for young children, elderly people, and
people with compromised immune systems.
Probiotics’ side effects, if they occur, tend to be mild and digestive (such as gas or bloating).
More serious effects have been seen in some people. Probiotics might theoretically cause
infections that need to be treated with antibiotics, especially in people with underlying health
conditions. They could also cause unhealthy metabolic activities, too much stimulation of the
immune system, or gene transfer (insertion of genetic material into a cell).
Probiotic products taken by mouth as a dietary supplement are manufactured and regulated as
foods, not drugs.
Some Other Points To Consider
• If you are thinking about using a probiotic product as CAM, consult your health care
provider first. No CAM therapy should be used in place of conventional medical care or to
delay seeking that care.
• Effects from one species or strain of probiotics do not necessarily hold true for others, or
even for different preparations of the same species or strain.
• If you use a probiotic product and experience an effect that concerns you, contact your
health care provider.
• You can locate research reports in peer-reviewed journals on probiotics’ effectiveness and
safety through the resources PubMed and CAM on PubMed.
NCCAM-Sponsored Research on Probiotics
Among recent NCCAM-sponsored research are the following projects:
• Investigators at Tulane University School of Public Health and Tropical Medicine are
studying the effectiveness of selected probiotic agents to treat diarrhea in undernourished
children in a developing country.
NCCAM-4
• At the Mayo Clinic College of Medicine, researchers have been examining probiotics for
possibly decreasing the levels of certain substances in the urine that can cause problems
such as kidney stones.
• A team at Tufts-New England Medical Center is studying probiotics for treating an
antibiotic-resistant type of bacteria that causes severe infections in people who are
hospitalized, live in nursing homes, or have weakened immune systems.
References
Sources are primarily recent reviews on the general topic of probiotics in the peer-reviewed
medical and scientific literature in English in the PubMed database, selected evidence-based
databases, and Federal Government sources.
1994-2004 U.S. specialty/other supplement sales. Nutrition Business Journal. 2005. Accessed at http://www.nutritionbusiness.com
on December 7, 2006.
Alvarez-Olmos MI, Oberhelman RA. Probiotic agents and infectious diseases: a modern perspective on a traditional
therapy. Clinical Infectious Diseases. 2001;32(11):1567-1576.
Bifidobacteria. Natural Medicines Comprehensive Database Web site. Accessed at http://www.naturaldatabase.com on
December 7, 2006.
Bifidus. Thomson MICROMEDEX AltMedDex System Web site. Accessed at http://www.micromedex.com on December 7, 2006.
Cabana MD, Shane AL, Chao C, et al. Probiotics in primary care pediatrics. Clinical Pediatrics. 2006;45(5):405-410.
Doron S, Gorbach SL. Probiotics: their role in the treatment and prevention of disease. Expert Review of Anti-Infective
Therapy. 2006;4(2):261-275.
Ezendam J, van Loveren H. Probiotics: immunomodulation and evaluation of safety and efficacy. Nutrition Reviews.
2006;64(1):1-14.
Food and Agriculture Organization (FAO) of the United Nations and World Health Organization (WHO). Guidelines for the
Evaluation of Probiotics in Food. Report of a Joint FAO/WHO Working Group on Drafting Guidelines for the Evaluation of Probiotics
in Food. Accessed at http://www.who.int/foodsafety/fs_management/en/probiotic_guidelines.pdf on December 7, 2006.
Gill HS, Guarner F. Probiotics and human health: a clinical perspective. Postgraduate Medical Journal. 2004;80(947):516-526.
Hammerman C, Bin-Nun A, Kaplan M. Safety of probiotics: comparison of two popular strains. BMJ.
2006;333(7576):1006-1008.
Huebner ES, Surawicz CM. Probiotics in the prevention and treatment of gastrointestinal infections. Gastroenterology
Clinics of North America. 2006;35(2):355-365.
Lactobacillus. Natural Medicines Comprehensive Database Web site. Accessed at http://www.naturaldatabase.com on
December 7, 2006.
Lactobacillus. Thomson MICROMEDEX AltMedDex System Web site. Accessed at http://www.micromedex.com on
December 7, 2006.
Probiotics: Bottom Line Monograph. Natural Standard Database Web site. Accessed at http://www.naturalstandard.com on
December 7, 2006.
Reid G, Hammond JA. Probiotics: some evidence of their effectiveness. Canadian Family Physician. 2005;51:1487-1493.
Salminen SJ, Gueimonde M, Isolauri E. Probiotics that modify disease risk.Journal of Nutrition . 2005;135(5):1294-1298.
Vanderhoof JA, Young RJ. Current and potential uses of probiotics. Annals of Allergy, Asthma, & Immunology.
2004;93(5 suppl 3):S33-S37.
Walker R, Buckley M. Probiotic Microbes: The Scientific Basis. Report of an American Society for Microbiology colloquium;
November 5-7, 2005; Baltimore, Maryland. American Society for Microbiology Web site. Accessed at
http://www.asm.org/academy/index.asp?bid=43351 on December 7, 2006.
NCCAM-5
----------------------- Page 6-----------------------
For More Information
NCCAM Clearinghouse
The NCCAM Clearinghouse provides information on CAM and NCCAM, including
publications and searches of Federal databases of scientific and medical literature. The
Clearinghouse does not provide medical advice, treatment recommendations, or referrals
to practitioners.
Toll-free in the U.S.: 1-888-644-6226
TTY (for deaf and hard-of-hearing callers): 1-866-464-3615
Web site: nccam.nih.gov
E-mail: info@nccam.nih.gov
PubMed®
A service of the National Library of Medicine (NLM), PubMed contains publication information
and (in most cases) brief summaries of articles from scientific and medical journals. CAM on
PubMed, developed jointly by NCCAM and NLM, is a subset of the PubMed system and focuses
on the topic of CAM.
Web site: www.ncbi.nlm.nih.gov/sites/entrez
CAM on PubMed: nccam.nih.gov/camonpubmed/
Acknowledgments
NCCAM thanks the following people for their technical expertise and review of this publication:
Carol Wells, Ph.D., University of Minnesota Medical School; Richard Oberhelman, M.D., Tulane
University School of Public Health and Tropical Medicine; Patricia Hibberd, M.D., Ph.D., Tufts-
New England Medical Center; Richard Walker, Ph.D., U.S. Food and Drug Administration; and
Marguerite Klein, M.S., R.D., and Jonathan (Josh) Berman, M.D., Ph.D., NCCAM.
This publication is not copyrighted and is in the public domain.
Duplication is encouraged.
NCCAM has provided this material for your information. It is not intended to substitute
for the medical expertise and advice of your primary health care provider. We encourage
you to discuss any decisions about treatment or care with your health care provider. The
mention of any product, service, or therapy is not an endorsement by NCCAM.
National Institutes of Health
???
U.S. Department of Health and Human Services
D345
Created January 2007
Updated August 2008
*D345*
web site with useful, free information:
http://www.alwaysfrugal.com/
Friday, August 7, 2009
Frigidaire Recalls Clothes Washers Due to Fire Hazard
http://www.cpsc.gov/cpscpub/prerel/prhtml09/09292.htmlNEWS from CPSC
U.S. Consumer Product Safety Commission
Office of Information and Public Affairs Washington, DC 20207
FOR IMMEDIATE RELEASE
July 30, 2009
Release # 09-292 Firm?s Recall Hotline: (800) 734-4519
CPSC Recall Hotline: (800) 638-2772
CPSC Media Contact: (301) 504-7908
Firm?s Media Contact: (614) 761-2633
Sear?s Recall Hotline: (888)-549-5870
Frigidaire Recalls Clothes Washers Due to Fire Hazard
WASHINGTON, D.C. - The U.S. Consumer Product Safety Commission, in cooperation with the firm named below, today announced a voluntary recall of the following consumer product. Consumers should stop using recalled products immediately unless otherwise instructed.
Name of Product: Crosley®, Frigidaire®, Kelvinator®, Kenmore®, Wascomat®, and White-Westinghouse® clothes washers
Units: About 35,000
Distributor: Frigidaire, of Cleveland, Ohio
Hazard: An internal defect in the washer?s drain pump can cause heat to build up, posing a fire hazard to the consumer.
Incidents/Injuries: No incidents or injuries have been reported.
Description: This recall involves the Crosley®, Frigidaire®, Kelvinator®, Kenmore®, Wascomat®, and White-Westinghouse® top load washers, 3.1 cubic foot front load washers and laundry centers.
Product Type Brand Model Serial Number
Top Load Washer Crosley, Frigidaire, Kelvinator,
White- Westinghouse
CTW100FW GLWS1749FS SWS833HS
FTW3011KW KWS1349DS SWX703HQ
FTW3014KW MWS939AS SWX703HS
FWS1233FS SWS1233HQ WWS833FS
FWS933FS SWS1233HS WWTW3000KW
GLWS1439FC SWS1339HS
GLWS1439FS SWS1649HS
XC90306228 to XC91606302
Front Load Washer Crosley, Frigidaire, Wascomat,
White- Westinghouse
CFW2000FW FTF530FS WE17N
FCCW3000FS GLTF1570FS WTF330HS
FTF1240FS WE17M
XC90501765 to XC91607678
Laundry Center Crosley, Frigidaire, Kenmore,
White -Westinghouse
97812 CLCE900FW GLET1142FS
97912 FEX831FS GLGH1642FS
97962 FGX831FS GLGT1031FS
C97812 FLGB8200FS GLGT1142FS
C97912 GCET1031FS MEX731CFS
C97962 GLEH1642FS SWSG1031HS
CLCE500FW GLET1031FS SWXG831HS
XE85104013 to XE91603486
*Not all serial numbers within these ranges are affected.
Model and serial numbers can be located as follows:
Top load washer = open the product?s lid, and the model and serial number are located inside the product?s lid, on the top, right hand corner.
Front load washer = open the door, and the model and serial number are located with other information at the top, center.
Laundry center = open the door to the dryer, and the model and serial number are located on the outer edge of the door nearest the door?s handle.
Sold by: Sears and other retailers nationwide from February 2009 through May 2009 for between $300 and $1100.
Manufactured in: United States
Remedy: Consumers should immediately unplug and stop using the machine. Consumers should contact Frigidaire or Sears (if unit was purchased there) to schedule a free repair.
Consumer Contact: For additional information, contact Frigidaire at (800) 734-4519 between 8 a.m. and 11 p.m. ET Monday through Saturday, or visit the firm?s Web site at www.laundrypumprecall.com. For consumers who purchased their product at Sears, call Sears toll free at (888) 549-5870 between 8 a.m. and 10 p.m. ET Monday through Saturday, or visit Sear?s Web site at www.sears.com
web site with useful info:
onlinerradiostations
http://www.onlineradiostations.com/
http://www.cpsc.gov/cpscpub/prerel/prhtml09/09292.htmlNEWS from CPSC
U.S. Consumer Product Safety Commission
Office of Information and Public Affairs Washington, DC 20207
FOR IMMEDIATE RELEASE
July 30, 2009
Release # 09-292 Firm?s Recall Hotline: (800) 734-4519
CPSC Recall Hotline: (800) 638-2772
CPSC Media Contact: (301) 504-7908
Firm?s Media Contact: (614) 761-2633
Sear?s Recall Hotline: (888)-549-5870
Frigidaire Recalls Clothes Washers Due to Fire Hazard
WASHINGTON, D.C. - The U.S. Consumer Product Safety Commission, in cooperation with the firm named below, today announced a voluntary recall of the following consumer product. Consumers should stop using recalled products immediately unless otherwise instructed.
Name of Product: Crosley®, Frigidaire®, Kelvinator®, Kenmore®, Wascomat®, and White-Westinghouse® clothes washers
Units: About 35,000
Distributor: Frigidaire, of Cleveland, Ohio
Hazard: An internal defect in the washer?s drain pump can cause heat to build up, posing a fire hazard to the consumer.
Incidents/Injuries: No incidents or injuries have been reported.
Description: This recall involves the Crosley®, Frigidaire®, Kelvinator®, Kenmore®, Wascomat®, and White-Westinghouse® top load washers, 3.1 cubic foot front load washers and laundry centers.
Product Type Brand Model Serial Number
Top Load Washer Crosley, Frigidaire, Kelvinator,
White- Westinghouse
CTW100FW GLWS1749FS SWS833HS
FTW3011KW KWS1349DS SWX703HQ
FTW3014KW MWS939AS SWX703HS
FWS1233FS SWS1233HQ WWS833FS
FWS933FS SWS1233HS WWTW3000KW
GLWS1439FC SWS1339HS
GLWS1439FS SWS1649HS
XC90306228 to XC91606302
Front Load Washer Crosley, Frigidaire, Wascomat,
White- Westinghouse
CFW2000FW FTF530FS WE17N
FCCW3000FS GLTF1570FS WTF330HS
FTF1240FS WE17M
XC90501765 to XC91607678
Laundry Center Crosley, Frigidaire, Kenmore,
White -Westinghouse
97812 CLCE900FW GLET1142FS
97912 FEX831FS GLGH1642FS
97962 FGX831FS GLGT1031FS
C97812 FLGB8200FS GLGT1142FS
C97912 GCET1031FS MEX731CFS
C97962 GLEH1642FS SWSG1031HS
CLCE500FW GLET1031FS SWXG831HS
XE85104013 to XE91603486
*Not all serial numbers within these ranges are affected.
Model and serial numbers can be located as follows:
Top load washer = open the product?s lid, and the model and serial number are located inside the product?s lid, on the top, right hand corner.
Front load washer = open the door, and the model and serial number are located with other information at the top, center.
Laundry center = open the door to the dryer, and the model and serial number are located on the outer edge of the door nearest the door?s handle.
Sold by: Sears and other retailers nationwide from February 2009 through May 2009 for between $300 and $1100.
Manufactured in: United States
Remedy: Consumers should immediately unplug and stop using the machine. Consumers should contact Frigidaire or Sears (if unit was purchased there) to schedule a free repair.
Consumer Contact: For additional information, contact Frigidaire at (800) 734-4519 between 8 a.m. and 11 p.m. ET Monday through Saturday, or visit the firm?s Web site at www.laundrypumprecall.com. For consumers who purchased their product at Sears, call Sears toll free at (888) 549-5870 between 8 a.m. and 10 p.m. ET Monday through Saturday, or visit Sear?s Web site at www.sears.com
web site with useful info:
onlinerradiostations
http://www.onlineradiostations.com/
Tuesday, August 4, 2009
August 4, 2009 security lapses at Ayala Center, Makati
Because of said security lapses at entrances to Glorietta, Park Square 1, SM Makati, dangerous weapons could have been brought into said areas, to the endangerment of shoppers in said areas.
On said date, at the Good Food section of said Glorietta, the door to the CR for the handicapped was defective. I had difficulty in unlocking said door.
I asked the person in charge of said room to show me his I.D., but he didn't show me his I.D. Also, at said Good Food section, I discovered a seller named San Sebastian. When I asked to see the sales invoice used by said seller, what was shown to bore not the Makati address but a Quezon City address.Whichever entity has jurisdiction over said Good Food section, allowing the use of said sales invoice with an address different from the address where said seller is an indication of an ani consumer attitude.
web site with free useful information:
helpguide org
http://helpguide.org/
kitchehintsandtips web site
http://www.kitchenhintsandtips.com/
websitetips web site
http://websitetips.com/
Because of said security lapses at entrances to Glorietta, Park Square 1, SM Makati, dangerous weapons could have been brought into said areas, to the endangerment of shoppers in said areas.
On said date, at the Good Food section of said Glorietta, the door to the CR for the handicapped was defective. I had difficulty in unlocking said door.
I asked the person in charge of said room to show me his I.D., but he didn't show me his I.D. Also, at said Good Food section, I discovered a seller named San Sebastian. When I asked to see the sales invoice used by said seller, what was shown to bore not the Makati address but a Quezon City address.Whichever entity has jurisdiction over said Good Food section, allowing the use of said sales invoice with an address different from the address where said seller is an indication of an ani consumer attitude.
web site with free useful information:
helpguide org
http://helpguide.org/
kitchehintsandtips web site
http://www.kitchenhintsandtips.com/
websitetips web site
http://websitetips.com/
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image of registry return receipt of letter addressed to Makati councilor J. J. Binay
